MOLECULAR BIOLOGY OF THE CELL

Course Description

CMB 702  Molecular Biology of the Cell (6 credit hours): Molecular Biology of the Cell is an online, asynchronous course with an emphasis on the structure, metabolism and biochemical function of major macromolecules (proteins, carbohydrates, lipids and nucleic acids). Bioenergetics, enzyme kinetics, cell signaling and regulation are studied at the molecular level. Emphasis is placed on cellular and physiological applications of biochemistry.

Apply the scientific method to generate, test, critique and refine (or abandon) hypotheses.
Summarize and explain the key tenants of cellular and molecular biology.
Describe the design and significance of cellular components and their interactions.
Describe basic genetic mechanisms.
Explain the importance of epigenetic factors to the cellular environment.
Describe the importance of the cellular environment for determining responses to changing cellular conditions.
Employ primary literature research to determine methods used to analyze novel and complex cellular systems.
Apply data analysis with multiple important practical applications that have arisen from the field of molecular biology.
Explain the role of the cell cycle in the development of cancer and outline treatments for different types of cancer.
Describe how cellular components communicate.

Note: The course topics listed below are for a regular fall or spring semester. The summer semester will be shortened to 10 weeks and several topics will be combined.

Topic	Dates*	Instructor
Proteins and Enzyme Kinetics	Dates*: Week 1	Instructor: Hennington
DNA, Chromosomes and Genomes	Dates*: Week 2	Instructor: Hennington
DNA Replication, Repair and Recombination	Dates*: Week 3	Instructor: Hennington
From DNA to Protein	Dates*: Week 4	Instructor: Hennington
Control of Gene Expression	Dates*: Week 5	Instructor: Hennington
Analyzing Cells, Molecules and Systems	Dates*: Week 6	Instructor: Hennington
Molecular Structure and Transport and Electrical Properties	Dates*: Week 7	Instructor: Hennington
Intracellular Compartments and Protein Sorting	Dates*: Week 8	Instructor: Hennington
Intracellular Vesicular Traffic	Dates*: Week 9	Instructor: Hennington
The Cytoskeleton	Dates*: Week 10	Instructor: Syed
Cell Communication	Dates*: Week 11	Instructor: Syed
Membrane Transport of Small Molecules	Dates*: Week 12	Instructor: Syed
Cell Junctions and the Extracellular Matrix	Dates*: Week 13	Instructor: Syed
The Cell Cycle and Cell Death (ROS and Cellular Death)	Dates*: Week 14	Instructor: Syed
Cancer	Dates*: Week 15	Instructor: Syed
Molecular and Cellular Evolution	Dates*: Week 16	Instructor: Syed
Development of Multicellular Organisms	Dates*: Week 17	Instructor: Syed