Course Description


CMB 708 Genetics, Development and Disease (3 credit hours) This project-based component will include studies in DNA repair mechanisms, the basis of selected genetic diseases and pedigree development, study of DNA mutations and treatment options for DNA-based diseases. Students will also explore how alteration of certain metabolic pathways relate to the development and progression of some human diseases. These projects will include the examination of regulations and ethics surrounding treatment and prevention of genetic diseases. Further, students will develop research, writing and presentation skills necessary for the work force.

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Course Information

Course Topics
Topics:** Research Project: Ethical Considerations of Genetic Diseases

Dates Assignment
IV.1. Autosomal Dominant and Recessive Inheritance Assignment: Pedigree Investigation
IV.2. Sex Linked and Nontraditional Modes of Inheritance Assignment: Colorblindness Study
IV.3 Clinical Cytogenetics and Disease Assignment: Karyotype Study
IV.4. Immunogenetics and Disease Assignment: Case Study: SCID – Baby Joe
IV.5. Genetic Basis of Development Assignment: Sonic Hedgehog and Holoprosencephaly
IV.6. Epigenetics Assignment: Smoking and Epigenetics (Collaborative)
IV.7. Genetic Variation Assignment: Hardy Weinberg Problem Set
IV.8. Multifactorial Inheritance and Common Disease Assignment: Alzheimer Disease and Schizophrenia
IV.9. Genetic Testing and Gene Therapy Assignment: CRISPR Study
IV.10. Genetics and Precision Medicine Assignment: GWAS Living in a Genomic World

**Assignments subject to change.

Quizzes: 15%
Projects (2): 30% (Rubrics will be used to grade each project)
Written Paper (1): 20%
Case Studies (4): 30% (Rubrics will be used to grade each case study)
Attendance: 5%

Students must maintain a 3.0/4.0 average in the Certificate Program.